Parallel Integrity Testing of Small Venting Filters
نویسنده
چکیده
Introduction Sterilizing grade venting filters are used to avoid the potential risk of airborne germs contaminating containers like fermentors or cell-culture vessels. Sterilizing grade filtration can only be guaranteed when the filters used are tested for integrity. Therefore , such filters are routinely tested by the bubble point or similar tests. Depending on the program settings and the actual bubble point (BP), it can easily take 10 – 20 min to perform one such test. When a large number of filters are used and tested every day, it makes sense to think about how to make the test procedure more efficient without increasing the risk of overlooking defective filters.
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